Unlocking the Secret to Skin Renewal: The Remarkable Beauty Benefits of RNA
From ancient plant extracts to modern biotechnology, humanity’s pursuit of beauty has never ceased. Today, we introduce a “star ingredient” from the life sciences—RNA (Ribonucleic Acid). Not only is it a vital molecule in cellular life processes, but with its exceptional repair and anti-aging capabilities, it is increasingly seen as the “future code” of high-end skincare.
PART 01
The Origin of RNA: A Gift from Life Sciences
RNA (Ribonucleic Acid) is a crucial molecule present in all living cells, playing essential roles in protein synthesis and gene regulation. With advancements in biotechnology, scientists have discovered that active RNA fragments (e.g., RNA-Na) derived from natural sources like yeast can be supplemented exogenously to act directly on skin cells, opening a new era of cellular-level repair in skincare.
PART 02
The Skincare Miracle of RNA: From Repair to Revitalization
01 The “Repair Specialist” against UV Damage
▷ Enhanced DNA repair: Supplies damaged cells with nucleotide raw materials, accelerating recovery from UV-induced DNA damage[1].
▷ Inhibits melanin production: Downregulates tyrosinase and MITF gene expression, limiting melanin production at the source[2-3], with effects comparable to traditional brightening ingredients like arbutin.
02 The “Time Reverser” for Anti-Aging
▷ Activates mitochondrial function: Boosts cellular energy metabolism, revitalize skin’s youthful appearance[5].
03 The All-Round Skincare Multitasker
▷ Deep hydration: Strengthens stratum corneum hydration capacity, improving xerosis and skin roughness[7].
PART 03
Breakthrough in RNA Technology: Lower Impurities, Better Solubility
The next-generation RNA-Na (W) utilizes proprietary purification technology to further eliminate residual colorants that were previously difficult to remove in conventional RNA. This advancement significantly improves solubility, enabling higher concentration formulations in cosmetics and skincare products, facilitating use in higher-concentration gelatin products and beverages, achieving “internal and external” health benefits.
PART 04
The Future is Here: Boundless Potential of RNA Skincare
From research labs to beauty counters, RNA is driving a revolution in skincare technology:
◎ Synergy with PDRN: When combined with PDRN (e.g., “Salmon DNA” therapy), it amplifies repair and regeneration.
◎ Sustainable sourcing: Extracted from Torula yeast, it offers both eco-friendly production and high efficacy, aligning with sustainable beauty trends.
RNA-based skincare represents more than an ingredient upgrade – it marks a shift in skincare philosophy—from “surface-level correction” to “cellular-level repair,” and from “single-function” to “internal-external synergy.” In today’s world of environmental stress and pollution, it offers a smarter, more holistic approach to skin health.
Restore Skin’s Primal Beauty
RNA-Na: Extracted from Torula yeast, polynucleotide content >90%. Ideal for serums, eye creams, and cosmetic fillers.
RNA-Na(W): Enhanced solubility, suitable for health beverages and gelatin supplements, delivering dual anti-aging benefits via oral and topical application.
Both products are registered on the Cosmetic Ingredient Safety Information Submission Platform and have official ingredient filing codes, ensuring full compliance with safety regulations.
Contact us to explore professional RNA skincare solutions!
References
[1] Xiang, Y., Laurent, B., Hsu, Ch et al.(2017).RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature,2017.
[2] Kim, N.H., et al. (2016). RNA interference-mediated knockdown of microphthalmia-associated transcription factor (MITF) inhibits melanogenesis in melan-a cells. Bioscience, Biotechnology, and Biochemistry, 80(5), 929-936.DOI: 10.1080/09168451.2015.1136883.
[3] Videira, I.F., et al. (2013). Tyrosinase mRNA is a target of miRNA-675-5p in human melanocytes.Pigment Cell & Melanoma Research, 26(4), 554-556.DOI: 10.1111/pcmr.12093.
[4] Kim, S., et al. (2019). Small interfering RNA-directed targeting of MMP1 gene expression suppresses UVB-induced skin photoaging.Journal of Dermatological Science, 93(1), 34-41.DOI: 10.1016/j.jdermsci.2018.12.004.
[5] Zhang, Y., et al. (2020). Mitochondria-targeted antisense RNA delivery for metabolic modulation.”Nature Communications, 11, 3230.DOI: 10.1038/s41467-020-17037-3.
[6]Chen, X., et al. (2018). Long non-coding RNA H19 regulates oxidative stress in UVB-irradiated keratinocytes. Journal of Cellular and Molecular Medicine, 22(9), 4245-4254.DOI: 10.1111/jcmm.13705.
[7]Bourguignon, L.Y., et al. (2013). Hyaluroman-CD44 interaction stimulates keratinocyte differentiation and filaggrin expression to promote epidermal barrier function.Journal of Investigative Dermatology, 133(5), 1358-1367.DOI: 10.1038/jid.2012.507.
For further information, please contact: info@gencloud-pharma.com
